November 1, 2019
United States Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, DC 20549
| Attention: | Sonia Bednarowski |
| Dietrich King |
| Re: | 89bio, Inc. |
| Registration Statement on Form S-1 (File No. 333-234174) |
Ladies and Gentlemen:
Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended, we wish to advise that between October 28, 2019 and the date hereof, approximately 1,700 copies of the Preliminary Prospectus, dated October 28, 2019, were distributed to prospective underwriters, institutional investors and prospective dealers in connection with the above-captioned Registration Statement.
We wish to advise you that the participating underwriters have informed us that they have complied and will continue to comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.
We hereby join in the request of the registrant that the effectiveness of the above-captioned Registration Statement, as amended, be accelerated to 4:00 p.m. Eastern Time, on Tuesday, November 5, 2019 or as soon thereafter as practicable.
[signature page follows]
| Very truly yours, | ||
| BOFA SECURITIES, INC. | ||
| SVB LEERINK LLC RBC CAPITAL MARKETS, LLC | ||
| As representatives of the Underwriters | ||
| By: | BOFA SECURITIES, INC. | |
| By: | /s/ Michelle A.H. Allong | |
| Name: | Michelle A.H. Allong | |
| Title: | Authorized Signatory | |
| By: | SVB LEERINK LLC | |
| By: | /s/ Murphy Gallagher | |
| Name: | Murphy Gallagher | |
| Title: | Managing Director | |
| By: | RBC CAPITAL MARKETS, LLC | |
| By: | /s/ Jennifer Caruso | |
| Name: | Jennifer Caruso | |
| Title: |
Managing Director | |
[Signature Page to Acceleration Request Letter]